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staining with anti sv2  (Developmental Studies Hybridoma Bank)


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    Developmental Studies Hybridoma Bank staining with anti sv2
    Motor function (latency to fall from an inverted screen) measured in 3-month-old WT, TDP43 Q331K/+ , LDHB MNKO and TDP43 Q331K/+ ; LDHB MNKO mice (A), electrophysiological recording performed on 3-month-old animals to determine the difference in CMAP at the ankle and sciatic notch ( B & C ) and Sensory Nerve Action Potential (SNAP) at the tail (n = 10-12) (D). NMJs on lumbrical muscles stained with <t>anti-NF,</t> <t>anti-SV2</t> and BTX to compare innervation of 3-month-old mice of different genotypes (n = 3; statistical comparison is between fully innervated endplates). Statistical significance was determined by pairwise Fisher’s exact tests on raw counts, with a Bonferroni correction applied for multiple comparisons. (E-I). Spinal cords stained to detect TDP43 and nuclei (DAPI) indicate no mislocalization in 6-month-old LDHB MNKO; TDP43 Q331K/+ or LDHB MNKO mice (J & K) . Representative images of 40x and 63x toluidine blue-stained sections of tibial nerves from 3-month-old animals (L-O) . Average g-ratio indicates no difference in degeneration between genotypes (n = 3). Unless otherwise mentioned, all statistical significance was determined by one-way ANOVA with Tukey’s multiple comparisons test (P) . ***p < 0.001, **p < 0.01.
    Staining With Anti Sv2, supplied by Developmental Studies Hybridoma Bank, used in various techniques. Bioz Stars score: 98/100, based on 1336 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/staining with anti sv2/product/Developmental Studies Hybridoma Bank
    Average 98 stars, based on 1336 article reviews
    staining with anti sv2 - by Bioz Stars, 2026-06
    98/100 stars

    Images

    1) Product Images from "Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline"

    Article Title: Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline

    Journal: PLOS One

    doi: 10.1371/journal.pone.0347135

    Motor function (latency to fall from an inverted screen) measured in 3-month-old WT, TDP43 Q331K/+ , LDHB MNKO and TDP43 Q331K/+ ; LDHB MNKO mice (A), electrophysiological recording performed on 3-month-old animals to determine the difference in CMAP at the ankle and sciatic notch ( B & C ) and Sensory Nerve Action Potential (SNAP) at the tail (n = 10-12) (D). NMJs on lumbrical muscles stained with anti-NF, anti-SV2 and BTX to compare innervation of 3-month-old mice of different genotypes (n = 3; statistical comparison is between fully innervated endplates). Statistical significance was determined by pairwise Fisher’s exact tests on raw counts, with a Bonferroni correction applied for multiple comparisons. (E-I). Spinal cords stained to detect TDP43 and nuclei (DAPI) indicate no mislocalization in 6-month-old LDHB MNKO; TDP43 Q331K/+ or LDHB MNKO mice (J & K) . Representative images of 40x and 63x toluidine blue-stained sections of tibial nerves from 3-month-old animals (L-O) . Average g-ratio indicates no difference in degeneration between genotypes (n = 3). Unless otherwise mentioned, all statistical significance was determined by one-way ANOVA with Tukey’s multiple comparisons test (P) . ***p < 0.001, **p < 0.01.
    Figure Legend Snippet: Motor function (latency to fall from an inverted screen) measured in 3-month-old WT, TDP43 Q331K/+ , LDHB MNKO and TDP43 Q331K/+ ; LDHB MNKO mice (A), electrophysiological recording performed on 3-month-old animals to determine the difference in CMAP at the ankle and sciatic notch ( B & C ) and Sensory Nerve Action Potential (SNAP) at the tail (n = 10-12) (D). NMJs on lumbrical muscles stained with anti-NF, anti-SV2 and BTX to compare innervation of 3-month-old mice of different genotypes (n = 3; statistical comparison is between fully innervated endplates). Statistical significance was determined by pairwise Fisher’s exact tests on raw counts, with a Bonferroni correction applied for multiple comparisons. (E-I). Spinal cords stained to detect TDP43 and nuclei (DAPI) indicate no mislocalization in 6-month-old LDHB MNKO; TDP43 Q331K/+ or LDHB MNKO mice (J & K) . Representative images of 40x and 63x toluidine blue-stained sections of tibial nerves from 3-month-old animals (L-O) . Average g-ratio indicates no difference in degeneration between genotypes (n = 3). Unless otherwise mentioned, all statistical significance was determined by one-way ANOVA with Tukey’s multiple comparisons test (P) . ***p < 0.001, **p < 0.01.

    Techniques Used: Muscles, Staining, Comparison



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    Motor function (latency to fall from an inverted screen) measured in 3-month-old WT, TDP43 Q331K/+ , LDHB MNKO and TDP43 Q331K/+ ; LDHB MNKO mice (A), electrophysiological recording performed on 3-month-old animals to determine the difference in CMAP at the ankle and sciatic notch ( B & C ) and Sensory Nerve Action Potential (SNAP) at the tail (n = 10-12) (D). NMJs on lumbrical muscles stained with <t>anti-NF,</t> <t>anti-SV2</t> and BTX to compare innervation of 3-month-old mice of different genotypes (n = 3; statistical comparison is between fully innervated endplates). Statistical significance was determined by pairwise Fisher’s exact tests on raw counts, with a Bonferroni correction applied for multiple comparisons. (E-I). Spinal cords stained to detect TDP43 and nuclei (DAPI) indicate no mislocalization in 6-month-old LDHB MNKO; TDP43 Q331K/+ or LDHB MNKO mice (J & K) . Representative images of 40x and 63x toluidine blue-stained sections of tibial nerves from 3-month-old animals (L-O) . Average g-ratio indicates no difference in degeneration between genotypes (n = 3). Unless otherwise mentioned, all statistical significance was determined by one-way ANOVA with Tukey’s multiple comparisons test (P) . ***p < 0.001, **p < 0.01.
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    Motor function (latency to fall from an inverted screen) measured in 3-month-old WT, TDP43 Q331K/+ , LDHB MNKO and TDP43 Q331K/+ ; LDHB MNKO mice (A), electrophysiological recording performed on 3-month-old animals to determine the difference in CMAP at the ankle and sciatic notch ( B & C ) and Sensory Nerve Action Potential (SNAP) at the tail (n = 10-12) (D). NMJs on lumbrical muscles stained with <t>anti-NF,</t> <t>anti-SV2</t> and BTX to compare innervation of 3-month-old mice of different genotypes (n = 3; statistical comparison is between fully innervated endplates). Statistical significance was determined by pairwise Fisher’s exact tests on raw counts, with a Bonferroni correction applied for multiple comparisons. (E-I). Spinal cords stained to detect TDP43 and nuclei (DAPI) indicate no mislocalization in 6-month-old LDHB MNKO; TDP43 Q331K/+ or LDHB MNKO mice (J & K) . Representative images of 40x and 63x toluidine blue-stained sections of tibial nerves from 3-month-old animals (L-O) . Average g-ratio indicates no difference in degeneration between genotypes (n = 3). Unless otherwise mentioned, all statistical significance was determined by one-way ANOVA with Tukey’s multiple comparisons test (P) . ***p < 0.001, **p < 0.01.
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    Motor function (latency to fall from an inverted screen) measured in 3-month-old WT, TDP43 Q331K/+ , LDHB MNKO and TDP43 Q331K/+ ; LDHB MNKO mice (A), electrophysiological recording performed on 3-month-old animals to determine the difference in CMAP at the ankle and sciatic notch ( B & C ) and Sensory Nerve Action Potential (SNAP) at the tail (n = 10-12) (D). NMJs on lumbrical muscles stained with <t>anti-NF,</t> <t>anti-SV2</t> and BTX to compare innervation of 3-month-old mice of different genotypes (n = 3; statistical comparison is between fully innervated endplates). Statistical significance was determined by pairwise Fisher’s exact tests on raw counts, with a Bonferroni correction applied for multiple comparisons. (E-I). Spinal cords stained to detect TDP43 and nuclei (DAPI) indicate no mislocalization in 6-month-old LDHB MNKO; TDP43 Q331K/+ or LDHB MNKO mice (J & K) . Representative images of 40x and 63x toluidine blue-stained sections of tibial nerves from 3-month-old animals (L-O) . Average g-ratio indicates no difference in degeneration between genotypes (n = 3). Unless otherwise mentioned, all statistical significance was determined by one-way ANOVA with Tukey’s multiple comparisons test (P) . ***p < 0.001, **p < 0.01.
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    Image Search Results


    Motor function (latency to fall from an inverted screen) measured in 3-month-old WT, TDP43 Q331K/+ , LDHB MNKO and TDP43 Q331K/+ ; LDHB MNKO mice (A), electrophysiological recording performed on 3-month-old animals to determine the difference in CMAP at the ankle and sciatic notch ( B & C ) and Sensory Nerve Action Potential (SNAP) at the tail (n = 10-12) (D). NMJs on lumbrical muscles stained with anti-NF, anti-SV2 and BTX to compare innervation of 3-month-old mice of different genotypes (n = 3; statistical comparison is between fully innervated endplates). Statistical significance was determined by pairwise Fisher’s exact tests on raw counts, with a Bonferroni correction applied for multiple comparisons. (E-I). Spinal cords stained to detect TDP43 and nuclei (DAPI) indicate no mislocalization in 6-month-old LDHB MNKO; TDP43 Q331K/+ or LDHB MNKO mice (J & K) . Representative images of 40x and 63x toluidine blue-stained sections of tibial nerves from 3-month-old animals (L-O) . Average g-ratio indicates no difference in degeneration between genotypes (n = 3). Unless otherwise mentioned, all statistical significance was determined by one-way ANOVA with Tukey’s multiple comparisons test (P) . ***p < 0.001, **p < 0.01.

    Journal: PLOS One

    Article Title: Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline

    doi: 10.1371/journal.pone.0347135

    Figure Lengend Snippet: Motor function (latency to fall from an inverted screen) measured in 3-month-old WT, TDP43 Q331K/+ , LDHB MNKO and TDP43 Q331K/+ ; LDHB MNKO mice (A), electrophysiological recording performed on 3-month-old animals to determine the difference in CMAP at the ankle and sciatic notch ( B & C ) and Sensory Nerve Action Potential (SNAP) at the tail (n = 10-12) (D). NMJs on lumbrical muscles stained with anti-NF, anti-SV2 and BTX to compare innervation of 3-month-old mice of different genotypes (n = 3; statistical comparison is between fully innervated endplates). Statistical significance was determined by pairwise Fisher’s exact tests on raw counts, with a Bonferroni correction applied for multiple comparisons. (E-I). Spinal cords stained to detect TDP43 and nuclei (DAPI) indicate no mislocalization in 6-month-old LDHB MNKO; TDP43 Q331K/+ or LDHB MNKO mice (J & K) . Representative images of 40x and 63x toluidine blue-stained sections of tibial nerves from 3-month-old animals (L-O) . Average g-ratio indicates no difference in degeneration between genotypes (n = 3). Unless otherwise mentioned, all statistical significance was determined by one-way ANOVA with Tukey’s multiple comparisons test (P) . ***p < 0.001, **p < 0.01.

    Article Snippet: Following three rinses with Phosphate buffered saline (PBS), lumbrical muscles were dissected for staining with anti-SV2 (Developmental Studies Hybridoma Bank AB2315387, 1:200), anti-2H3 (Developmental Studies Hybridoma Bank AB2314897, 1:100) and α-bungarotoxin (BTX) (Biotium 00006, 1:500) as described previously [ ].

    Techniques: Muscles, Staining, Comparison